The Browndove BD140P is a single-use, low-flux dialyzer for hemodialysis, featuring a 1.4 square meter surface area, a polyethersulfone (PES) membrane, and sterile, non-pyrogenic fluid pathways. It’s designed for use in controlled ultrafiltration dialysis systems. The dialyzer is housed in medical-grade polycarbonate and is sterilized using gamma radiation.
Biocompatibility
1.Polyethersulfone Membrane: PES membranes are known for their excellent biocompatibility, which reduces the risk of inflammatory reactions during dialysis treatments.
2.Surface Modification: Some PES dialyzers incorporate surface-modifying agents to further enhance biocompatibility by reducing protein adsorption and platelet adhesion.
3.Gamma Sterilization: The BD140P dialyzer is sterilized using gamma radiation, a method that minimizes the risk of toxic residues and maintains the integrity of the membrane.
Safety Considerations
1.First-Use Reactions: Some patients may experience first-use reactions due to residual endotoxins or other substances from the manufacturing process. Pre-conditioning the dialyzer by filling it with a sterilizing solution before the initial use can help mitigate these reactions.
2.Material Safety: The BD140P dialyzer is housed in a medical-grade polycarbonate shell, which is designed to withstand sterilization processes and minimize the risk of material degradation.
Clinical Application
The BD140P dialyzer is utilized in hemodialysis treatments to filter waste, toxins, and excess fluids from the blood of patients with impaired kidney function. Its polyethersulfone membrane offers enhanced biocompatibility and effective solute clearance.
